Concerns from Vietnam veterans about their own—and their children’s—health, as well as emerging evidence on ill effects of exposure to Agent Orange, led Congress to enact the Agent Orange Act of 1991. This legislation directed the U.S. Department of Veterans Affairs (VA) to ask the National Academies of Sciences, Engineering, and Medicine to comprehensively evaluate scientific and medical information regarding the health effects of exposure to Agent Orange, other herbicides used in Vietnam, and the various components of those herbicides, including TCDD. The first report, Veterans and Agent Orange: Health Effects of Herbicides Used in Vietnam (VAO), was published in 1994, and Congressionally mandated updates have been published approximately every 2 years since.
This report, Veterans and Agent Orange: Update 11 (2018), presents the committee’s analysis of peer-reviewed, scientific reports published between September 30, 2014, and December 31, 2017, about associations between various health outcomes and exposure to TCDD and other chemicals in the herbicides used in Vietnam. The report also takes into account information from the existing evidence base.