Publication

Guiding Principles for Developing Dietary Reference Intakes Based on Chronic Disease


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For decades, nutrient intake recommendations have been issued through the Dietary Reference Intakes (DRIs) established by consensus committees of the Institute of Medicine, and now the National Academies of Sciences, Engineering, and Medicine (the National Academies). For each nutrient (e.g., vitamins, minerals, water, electrolytes, carbohydrate, or protein) deemed essential, DRI committees reviews the scientific literature to help inform nutrition standards of adequacy and toxicity for groups of people of different genders and at different life stages. These DRIs are used for planning and assessing the diets of apparently healthy individuals and groups. The National Academies convened an ad hoc committee to determine guiding principles to support future DRI committees as they make decisions about recommending DRIs for specific nutrients or other food substances (NOFSs) that could ameliorate the risk of chronic disease. The resulting report, Guiding Principles for Developing Dietary Reference Intakes Based on Chronic Disease, addresses conceptual and methodological challenges and offers recommendations and guiding principles to develop DRIs based on chronic disease endpoints

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