Ranking Vaccines Applications of a Prioritization Software Tool Phase III: Use Case Studies and Data Framework


At the request of the National Vaccine Program Office of the Department of Health and Human Services, the Institute of Medicine (IOM) initiated a sequence of projects in early 2011 to help provide guidance in prioritizing new vaccines for development. This effort has proceeded in three phases, each building upon the key objective of the U.S. National Vaccine Plan: “Develop a catalogue of priority vaccine targets of domestic and global health importance.” The result of this unique effort is the Strategic Multi-Attribute Ranking Tool for Vaccines—or SMART Vaccines—a novel software tool to facilitate stakeholder discussions and decisions on vaccine research and development priorities. 

In the Phase III work, the IOM in partnership with the National Academy of Engineering enhanced SMART Vaccines—version 1.1 of the software can be downloaded for free from The supporting report, Ranking Vaccines: Applications of a Prioritization Software Tool, describes: (1) the evaluation of the software in international user-based applications, (2) a general data framework for the software, and (3) the next steps that would increase the use and value of SMART Vaccines.