Publications from the National Academies of Sciences, Engineering, and Medicine provide objective and straightforward advice to decision makers and the public. This site includes Health and Medicine Division (HMD) publications released after 1998. A complete list of HMD’s publications from its establishment in 1970 to the present is available as a PDF.
Glutamate-Related Biomarkers in Drug Development for ...
Released: June 08, 2011
Problems with how the neurotransmitter glutamate functions in the brain have been linked to a wide variety of disorders, including schizophrenia, Alzheimer’s, substance abuse, and traumatic brain injury. Efforts to understand, treat, and prevent glutamate-related disorders can be aided by the identification of valid biomarkers. The IOM’s Forum on Neuroscience and Nervous System Disorders held a workshop June 21-22, 2010, to explore ways to accelerate the development, validation, and implementation of such biomarkers.
Sex Differences and Implications for Translational ...
Released: December 10, 2010
Biological differences between the sexes influence not only individual health but also public health, biomedical research, and health care. The IOM held a workshop March 8-9, 2010, to discuss sex differences and their implications for translational neuroscience research, which bridges the gap between scientific discovery and application.
Future Opportunities to Leverage the Alzheimer's Disease ...
Released: December 10, 2010
Nearly 5.3 million Americans are living with Alzheimer’s disease, and 26.6 million people are affected worldwide. The Alzheimer’s Disease Neuroimaging Initiative (ADNI), a public-private partnership, provides a publicly available, international database of clinical and imaging data to foster research and collaboration on Alzheimer’s research worldwide. The IOM held a workshop on July 12, 2010, to explore opportunities to use information from and partnerships formed because of ADNI to continue to improve the understanding and treatment of Alzheimer’s disease.
The Science of Adolescent Risk-Taking - Workshop Summary ...
Released: December 01, 2010
Adolescence is a time when youth make decisions, both good and bad, that have consequences for the rest of their lives. Some of these decisions put them at risk of lifelong health problems, injury, or death. The IOM held three public workshops between 2008 and 2009 to provide a venue for researchers, health care providers, and community leaders to discuss strategies to improve adolescent health.
Mental, Neurological, and Substance Use Disorders in Sub ...
Released: July 08, 2010
Millions of people in sub-Saharan Africa suffer from mental, neurological, and substance use (MNS) disorders, and most do not have the resources to obtain treatment. The Uganda National Academy of Sciences and the IOM hosted a workshop to discuss the state of care for MNS disorders in sub-Saharan Africa.
CNS Clinical Trials: Suicidality and Data Collection ...
Released: May 04, 2010
The Food and Drug Administration (FDA) now requires that all clinical trials for drugs that affect the central nervous system—including psychiatric drugs—are assessed for whether that drug might cause suicidal ideation or behavior. The IOM’s Forum on Neuroscience and Nervous System Disorders hosted a meeting on June 26, 2009, to discuss the FDA’s new policy and how to analyze best whether suicidal thoughts predict actual suicidal behavior in the near future.
Preliminary Assessment of Readjustment Needs of Veterans ...
Released: March 31, 2010
Nearly 1.9 million U.S. troops have been deployed to Afghanistan and Iraq since October 2001. Many service members and veterans face serious challenges in readjusting to normal life after returning home. This initial report presents findings on the most critical challenges, and lays out the blueprint for the second phase of the study to determine how best to meet the needs of returning troops and their families.
Provision of Mental Health Counseling Services under ...
Released: February 12, 2010
In this report, the IOM makes recommendations for permitting independent practice for mental health counselors treating patients within TRICARE—the DOD’s health care benefits program. This would change current policy, which requires all counselors to practice under a physician’s supervision without regard to their education, training, licensure or experience.
Depression in Parents, Parenting, and Children: Opportunities ...
Released: June 09, 2009
Depression is a widespread condition affecting approximately 7.5 million parents in the U.S. each year and may be putting at least 15 million children at risk for adverse health outcomes. Based on evidentiary studies, major depression in either parent can interfere with parenting quality and increase the risk of children developing mental, behavioral and social problems. Depression in Parents, Parenting, and Children highlights disparities in the prevalence, identification, treatment, and prevention of parental depression among different sociodemographic populations. It also outlines strategies for effective intervention and identifies the need for a more interdisciplinary approach that takes biological, psychological, behavioral, interpersonal, and social contexts into consideration.
Preventing Mental, Emotional, and Behavioral Disorders ...
Released: March 12, 2009
Mental health and substance use disorders among children, youth, and young adults are major threats to the health and well-being of younger populations which often carryover into adulthood. The costs of treatment for mental health and addictive disorders, which create an enormous burden on the affected individuals, their families, and society, have stimulated increasing interest in prevention practices that can impede the onset or reduce the severity of the disorders. Preventing Mental, Emotional, and Behavioral Disorders Among Young People updates a 1994 Institute of Medicine book, Reducing Risks for Mental Disorders, focusing on the research base and program experience with younger populations that have emerged since that time.