About Publications

Publications from the National Academies of Sciences, Engineering, and Medicine provide objective and straightforward advice to decision makers and the public. This site includes Health and Medicine Division (HMD) publications released after 1998. A complete list of HMD’s publications from its establishment in 1970 to the present is available as a PDF.


  • Transforming Health Care Scheduling and Access: Getting to ... Released: June 29, 2015
    The Institute of Medicine (IOM) report Crossing the Quality Chasm identified six fundamental aims for health care—that it be safe, effective, patient-centered, efficient, equitable, and timely. Of these fundamental aims, timeliness is in some ways the least well studied and understood. How can timely care be ensured in various health care settings, and what are some of the reasons that care is sometimes not timely? The report presented here was developed by the IOM Committee on Optimizing Scheduling in Health Care to answer such questions.
  • Developing a 21st Century Neuroscience Workforce ... Released: April 21, 2015
    Given the changing landscape resulting from technological advances and the growing importance of interdisciplinary and collaborative science, the Institute of Medicine’s (IOM’s) Forum on Neuroscience and Nervous System Disorders convened a workshop on October 28 and 29, 2014, in Washington, DC, to explore future workforce needs and how these needs should inform training programs.
  • Policy Issues in the Development and Adoption of Biomarkers ... Released: April 02, 2015
    A long-held goal in oncology has been to develop therapies that target the specific abnormalities in each patient’s cancer rather than simply treating cancers based on the tissue of origin. In the past decade, advances in technology have enabled researchers to relatively quickly and inexpensively determine, in minute detail, the genetic makeup of tumors.However, many challenges remain in effectively and efficiently developing new targeted cancer therapies and the biomarker tests that indicate which patients will be responsive to them, and in implementing them appropriately in clinical practice. These challenges include many policy issues, such as the level of oversight needed for test development and use, levels of evidence necessary for reimbursement decisions, and ways to meet informational needs of patients and care providers.
  • The Neuroscience of Gaming: Workshop in Brief : Health and ... Released: February 02, 2015
    More than 1.2 billion people worldwide play video games (online, via console, mobile phone, and other wireless devices), and many may be unaware that programmers often incorporate neuroscience into game design. Given the high prevalence of gaming in today’s society, the Institute of Medicine (IOM) Forum on Neuroscience and Nervous System Disorders hosted the Social Issues Roundtable at the Society for Neuroscience annual meeting on November 16, 2014, in Washington, DC, to explore the neuroscience of video games, with emphasis on relevant scientific, ethical,and societal issues.
  • Sharing Clinical Trial Data: Maximizing Benefits, Minimizing ... Released: January 14, 2015
    In its report, Sharing Clinical Trial Data: Maxi­mizing Benefits, Minimizing Risk, the committee concludes that sharing data is in the public interest, but a multi-stakeholder effort is needed to develop a culture, infrastructure, and policies that will foster responsible sharing—now and in the future.
  • Advancing Therapeutic Development for Dry Age-Related ... Released: January 02, 2015
    Age-related macular degeneration (AMD) is the leading cause of blindness among white Americans and others of European descent, with lower prevalence among those of Asian, Latino, or African ancestry. The overall prevalence of AMD is approximately 8.7 percent worldwide and is expected to rise to 196 million people worldwide by 2020 and 288 million by 2040 (Wong et al., 2014). AMD typically affects people age 50 and older, and the prevalence increases with age, particularly after the age of 75.
  • Ensuring Patient Access to Affordable Cancer Drugs ... Released: November 10, 2014
    To explore the issue of cancer drug costs and patient access to affordable, appropriate drug therapies, the NCPF convened a workshop on ensuring patient access to affordable cancer drugs on June 9, 2014, in Washington, DC.
  • Integrating Research and Practice: Health System Leaders ... Released: September 23, 2014
    In April and June 2014 the Institute of Medicine’s (IOM) Roundtable on Value & Science-Driven Health Care convened two workshops aimed at accelerating progress toward real-time knowledge generation through the seamless integration of clinical practice and research, one of the fundamental concepts of a continuously learning health system. These meetings were sponsored by the Patient-Centered Outcomes Research Institute, and prompted by the development of the PCORnet and similar efforts to accelerate real-time learning. A major premise that served as the foundation for the two workshops is that the continuous and seamless assessment of the effectiveness and efficiency of care is basic to a continuously learning and constantly improving health care system. This publication summarizes the presentations and discussions that occurred during the two workshops, highlighting the key lessons presented, practical strategies, and the needs and opportunities for future leadership.
  • Improving Access to Essential Medicines for Mental ... Released: July 14, 2014
    Recognizing the limitations of most SSA countries to effectively treat MNS disorders, the Forum on Neuroscience and Nervous System Disorders of the Institute of Medicine convened a workshop in Addis Ababa, Ethiopia, in January 2014. The workshop brought together key stakeholders to discuss opportunities for achieving long-term affordable access to medicines for MNS disorders and to consider frameworks and strategies that have been successful in other countries and for different diseases. In particular, the workshop was organized around a series of focused discussions on four challenge areas: insufficient demand, inappropriate selection, ineffective supply chains, and high pricing and poor financing. This document summarizes the workshop.
  • Contemporary Issues for Protecting Patients in Cancer ... Released: July 02, 2014
    On February 24 and 25, 2014, the National Cancer Policy Forum of the Institute of Medicine convened a workshop to frame and discuss contemporary issues in human subjects protections as they pertain to cancer research, with the goal of identifying potential relevant policy actions. This document summarizes the workshop.