Publications from the National Academies of Sciences, Engineering, and Medicine provide objective and straightforward advice to decision makers and the public. This site includes Health and Medicine Division (HMD) publications released after 1998. A complete list of HMD’s publications from its establishment in 1970 to the present is available as a PDF.
Improving and Accelerating Therapeutic Development for ...
Released: November 25, 2013
Although there is a high burden associated with nervous system disorders, development of new therapeutics remains stagnant. Over the last decade, fewer new drugs for nervous system disorders have garnered approval in comparison to other therapeutic areas. Current data suggest that drug development, from the start of a discovery program to regulatory approval, can take an average of 12 to 15 years. Building off of concepts discussed at a 2012 IOM workshop, the IOM Forum on Neuroscience and Nervous System Disorders held a workshop to examine opportunities to accelerate early phases of drug development for nervous system drug discovery.
Creating Equal Opportunities for a Healthy Weight - Workshop ...
Released: November 25, 2013
The 2012 IOM report Accelerating Progress in Obesity Prevention identified five environments in which change is needed to accelerate progress in obesity prevention. Each of these settings -physical activity, food and beverage, messaging, health care and worksites, and schools– interact with the others, creating a set of interconnected systems that can be changed only through engagement, leadership, and action among many groups and at many levels. The IOM Standing Committee on Childhood Obesity Prevention held a workshop to examine the role of the many factors that contribute to health disparities and to explore ways to create equity.
Identifying and Addressing the Needs of Adolescents and ...
Released: November 04, 2013
Cancer is the leading disease-related cause of death in adolescents and young adults (AYAs). Each year, nearly 70,000 AYAs between the ages of 15 and 39 are diagnosed with cancer. Adolescents and young adults face a variety of unique short- and long-term health and psychosocial issues. Many programs for cancer treatment, survivorship care, and psychosocial support do not focus on the specific needs and risks of AYA cancer patients. The IOM’s National Cancer Policy Forum held a workshop to facilitate discussion about gaps and challenges in caring for AYA cancer patients and potential strategies and actions to improve the quality of their care.
Neurodegeneration: Exploring Commonalities Across ...
Released: October 03, 2013
Neurodegenerative diseases – such as Alzheimer’s disease, Parkinson’s disease, amyotrophic lateral sclerosis (ALS), and frontotemporal dementia (FTD) – are becoming increasingly more prevalent in the United States due to the aging population. Implications of these diseases are grave, both for individual and family quality of life and for healthcare costs. Recent findings have revealed potential commonalities and parallelisms in genetic and cellular mechanisms across neurodegenerative diseases. In 2012, the IOM hosted a workshop to explore commonalities across neurodegenerative diseases and to identify potential opportunities for collaboration across the respective research and development communities.
Strengthening Human Resources Through Development of ...
Released: August 14, 2013
Sub-Saharan Africa has one of the largest treatment gaps for mental, neurological, and substance use (MNS) disorders in the world. The ability to provide adequate human resources for the delivery of essential interventions for MNS disorders is a critical barrier to bridging the treatment gap. In 2012, the IOM hosted a second workshop in Kampala, Uganda, to discuss candidate core competencies that providers might need to help ensure the effective delivery of services for MNS disorders. The workshop focused on candidate competencies for four MNS disorders that account for the greatest burden in low- and middle-income countries: depression, psychosis, epilepsy, and alcohol use disorders.
Implementing a National Cancer Clinical Trials System for the ...
Released: July 15, 2013
Recognizing the recent transformative advances in cancer research that necessitate modernization in how cancer clinical trials are run, as well as inefficiencies and other challenges impeding the national cancer clinical trials program, the National Cancer Institute asked the IOM to develop a set of recommendations to improve the federally funded cancer clinical trials system. These recommendations were published in a 2010 IOM report. In 2011, the IOM’s National Cancer Policy Forum (NCPF) held a workshop to engage stakeholders in discussions about the changes they planned to implement in response to the IOM report. Two years later, the NCPF held a second workshop in which stakeholders reported the changes that they have made thus far to address the IOM recommendations, and discussed additional actions needed to improve the system.
The Science and Applications of Microbial Genomics ...
Released: April 03, 2013
Over the past several decades, new scientific tools and approaches for detecting microbial species have dramatically enhanced our understanding of the microbial flora and fauna and their dynamic interactions with the environments in which they reside. In June 2012, the IOM Forum on Microbial Threats convened a public workshop to discuss the scientific tools and approaches being used for detecting and characterizing microbial species, and the roles of microbial genomics and metagenomics to better understand the culturable and unculturable microbial world around us.
Challenges and Opportunities for Change in Food Marketing ...
Released: March 04, 2013
The childhood obesity epidemic is an urgent public health problem, and it will continue to take a substantial toll on the health of Americans. The most recent data show that almost a third of U.S. children and adolescents are overweight or obese. Children are exposed to an enormous amount of commercial advertising and marketing for food. In 2009, children age 2-11 saw and average of more than 10 television food ads per day. The marketing of high-calorie, low-nutrient foods and beverages is linked to overweight and obesity. The IOM hosted a workshop which examined contemporary trends in marketing of foods and beverages to children and youth and the implications of those trends for obesity prevention.
Evaluation of PEPFAR : Health and Medicine Division
Released: February 20, 2013
Through the President’s Emergency Plan for AIDS Relief (PEPFAR), the United States has provided an unprecedented level of health and development assistance and health diplomacy around the world. PEPFAR has saved and improved the lives of millions of people; supported HIV prevention, care, and treatment; strengthened systems; and engaged with partner countries to facilitate HIV policy and planning for sustainable responses to their epidemic. The IOM evaluation drew upon a variety of data sources, including quantitative data, extensive document review, and primary qualitative data collection through more than 400 interviews, including some site visits, with diverse stakeholders in 13 PEPFAR partner countries, at PEPFAR’s headquarters, and at other institutions and agencies involved in the global HIV response.
Delivering Affordable Cancer Care in the 21st Century ...
Released: February 11, 2013
Spending on health care currently accounts for 18 percent of the United States’ GDP. By 2037, that percentage is expected to increase to 25 percent of GDP. Spending on cancer care is expected to increase because of the rapid influx of new cancer diagnoses as the population ages. Also, as more expensive therapies and technologies become the standard of care, there are concerns that the costs of cancer treatment could begin to outpace health care inflation as a whole. The IOM held a workshop to examine the drivers of current and projected cancer care costs as well as potential ways to curb these costs while maintaining or improving the quality of care.