Publications from the National Academies of Sciences, Engineering, and Medicine provide objective and straightforward advice to decision makers and the public. This site includes Health and Medicine Division (HMD) publications released after 1998. A complete list of HMD’s publications from its establishment in 1970 to the present is available as a PDF.
Impact of the Global Medical Supply Chain on SNS ...
Released: July 18, 2018
An ad hoc committee organized a public workshop, held on August 28, 2017, to explore the current state of the global supply chain as it relates to Strategic National Stockpile (SNS) assets, and the role of communications in mitigating supply chain risks in enhancing the resilience of medical countermeasure (MCM) distribution efforts.
Examining the Impact of Real-World Evidence on Medical ...
Released: July 11, 2018
Workshop two took place on March 6–7, 2018. This “town-hall” style meeting included in-depth audience discussions and active participation that illuminated the types of data that are appropriate for what specific purposes and suggest practical approaches for data collection and evidence use by developing and working through example use cases.
Returning Individual Research Results to Participants ...
Released: July 10, 2018
An ad hoc committee reviewed the current evidence on the benefits, harms, and costs of returning individual research results, while also considering the ethical, social, operational, and regulatory aspects of the practice.
Neuroforensics: Exploring the Legal Implications of Emerging ...
Released: July 06, 2018
On March 6, 2018, the Forum on Neuroscience and Nervous System Disorders, in collaboration with the Committee on Science, Technology, and Law (CSTL), held a public workshop to explore and advance efforts to identify and evaluate the potential effects of emerging neurotechnologies on the legal system.
Physician-Assisted Death: Scanning the Landscape ...
Released: June 27, 2018
As a matter of public opinion and of public policy, a national dialogue is taking place around the question of whether, and under what circumstances, terminally ill patients can access life-ending medications with the aid of a physician. This publication summarizes the presentations and discussions from a workshop of the National Academies of Sciences, Engineering, and Medicine. The workshop explored what is known and not known empirically about the practice of physician-assisted death, as well as some of the moral and ethical considerations regarding the practice.
Financing and Payment Strategies to Support High-Quality ...
Released: May 16, 2018
Those facing serious illness have a range of interconnected medical and non-medical needs, and the way their care is financed has a large impact on the care they receive. Medicare is the predominant payer, but both Medicaid and private payers also play significant roles in financing care for serious illness. In an effort to address the complex needs of people with serious illness, public and private health care payers are testing innovative financing strategies and alternative payment models.
Advancing Therapeutic Development for Pain and Opioid Use ...
Released: March 23, 2018
Chronic pain is one of the most prevalent, costly, and disabling health conditions in the United States. In parallel with increasing recognition of the need to treat chronic pain, the opioid epidemic has emerged as a growing public health emergency. In 2017, the National Institutes of Health began exploring public-private partnerships to develop solutions to the opioid crisis and cut in half the time it takes to develop non-addictive analgesics. To help inform this effort, the National Academies’ Forum on Neuroscience and Nervous Systems Disorders hosted a public workshop that brought together experts and stakeholders from academia, federal agencies, advocacy organizations, and companies developing therapeutics for pain and opioid use disorders.
Implementing and Evaluating Genomic Screening Programs ...
Released: March 16, 2018
Genomic applications are being integrated into a broad range of clinical and research activities at health care systems across the United States. The genomics-based screening programs are clinical screening programs that examine genes or variants in unselected populations in order to identify individuals who are at an increased risk for a particular health concern (e.g., diseases, adverse drug outcomes) and who might benefit from clinical interventions.
Aging and Disability: Beyond Stereotypes to Inclusion ...
Released: March 13, 2018
How do stereotypes affect the health and independence of aging adults and those with disabilities? How do they impact the industries that interact with these populations? And what are some opportunities to disrupt the narrative and change perceptions of what it means to be older or have a disability?
Enabling Novel Treatments for Nervous System Disorders by ...
Released: March 08, 2018
The blood-brain barrier (BBB) presents a special challenge to the development of therapeutics for many central nervous system (CNS) disorders. Far from acting simply as a physical barrier, the BBB is a complex dynamic system involving several cell types, passive and active transport mechanisms, and adaptive function to control the exchange of substances between the blood and the CNS. Few therapeutic agents readily traverse the BBB to reach the brain or spinal cord, including most small molecule drugs and the vast majority of large molecules such as proteins.