Publications from the National Academies of Sciences, Engineering, and Medicine provide objective and straightforward advice to decision makers and the public. This site includes Health and Medicine Division (HMD) publications released after 1998. A complete list of HMD’s publications from its establishment in 1970 to the present is available as a PDF.
Exploring the Translation of the Results of Hurricane Sandy ...
Released: September 15, 2017
The workshop Translating the Results of Hurricane Sandy Research Grants into Policy and Operations was convened on July 20, 2017, in Washington, DC, by the Health and Medicine Division of the National Academies of Sciences, Engineering, and Medicine with the objective of exploring key findings from published Hurricane Sandy research grant projects, examining the impact of the scientific findings on disaster policy and operations, and discussing opportunities to translate the research findings to future preparedness response and recovery efforts.
Biomarkers of Neuroinflammation: Proceedings of a Workshop ...
Released: September 15, 2017
Innate and adaptive immunity have become very important areas of investigation for psychiatric, neurologic, and neurodevelopmental disorders, and neurodegeneration resulting from traumatic brain injury. To address these gaps in understanding mechanisms and how to translate that understanding into therapeutics, the Forum on Neuroscience and Nervous System Disorders of the National Academies of Sciences, Engineering, and Medicine convened a workshop on March 20–21, 2017, bringing together key leaders in the field from industry, academia, and governmental agencies to explore the role and mechanisms of neuroinflammation in a variety of central nervous system diseases.
Guiding Principles for Developing Dietary Reference Intakes ...
Released: August 03, 2017
For decades, nutrient intake recommendations have been issued through the Dietary Reference Intakes (DRIs) established by consensus committees of the Institute of Medicine, and now the National Academies of Sciences, Engineering, and Medicine (the National Academies). For each nutrient (e.g., vitamins, minerals, water, electrolytes, carbohydrate, or protein) deemed essential, DRI committees reviews the scientific literature to help inform nutrition standards of adequacy and toxicity for groups of people of different genders and at different life stages. These DRIs are used for planning and assessing the diets of apparently healthy individuals and groups.
Building Communication Capacity to Counter Infectious ...
Released: June 16, 2017
Building communication capacity is a critical piece of preparing for, detecting, and responding to infectious disease threats. Various organizations, including CDC (2011) and WHO (2008), have provided guidance on developing frameworks, standards, protocols, and conceptual approaches to communicating critical information during infectious disease outbreaks. Furthermore, governments and nongovernmental organizations have developed and implemented plans to address the gaps in communication capacity during these situations.
Integrating Clinical Research into Epidemic Response: The ...
Released: April 12, 2017
The 2014 Ebola epidemic in western Africa was the longest and deadliest Ebola outbreak in history, resulting in 28,616 cases and 11,310 deaths. In the midst of the rapidly spreading, highly dangerous contagious disease—with no Ebola-specific vaccines or therapeutics available to help curb the epidemic—the international community implemented clinical trials on investigational agents, not yet studied in humans for safety or efficacy.
A National Strategy for the Elimination of Hepatitis B and C ...
Released: March 28, 2017
Each year, hepatitis B virus and hepatitis C virus cause nearly 1.5 million deaths worldwide—more than HIV, tuberculosis, and malaria. Such loss of life comes at a cost to society through the direct expense of treatment as well as through the loss of adults in their prime. In an effort to describe a strategy for eliminating viral hepatitis as a U.S. public health problem by 2030, the National Academies, with support from the Centers for Disease Control and Prevention and the U.S. Department of Health and Human Services, the American Association for the Study of Liver Diseases, the Infectious Diseases Society of America, and the National Viral Hepatitis Roundtable, convened an expert committee to outline a national strategy.
Therapeutic Development in the Absence of Predictive Animal ...
Released: March 10, 2017
Despite the high prevalence and burden of nervous system disorders, development of new therapeutics lags behind other disease areas. Gaps in understanding the underlying pathophysiology, a dearth of biomarkers, and limitations in the capacity of animal models to predict drug efficacy for human brain disorders have contributed to a high rate of late stage failures in drug development and decreased investment in neuroscience research programs at pharmaceutical companies. On September 12-13, 2016, the National Academies of Sciences, Engineering, and Medicine’s Forum on Neuroscience and Nervous System Disorders hosted a public workshop to explore opportunities to accelerate drug development absent predictive animal models.
International Perspectives on Integrating Ethical, Legal, and ...
Released: January 09, 2017
Emerging neurotechnologies—devices and techniques designed to collect information about the brain or affect its function—are becoming increasingly important due to scientific and technological advances and a persistent need to develop effective therapies to address the large global burden of neurological and psychiatric disease. The Organisation for Economic Co-operation and Development (OECD)—in collaboration with Arizona State University and the National Academies of Sciences, Engineering, and Medicine—held a workshop in Washington, DC, on Neurotechnology and Society: Strengthening Responsible Innovation in Brain Science.
Big Data and Analytics for Infectious Disease Research ...
Released: December 08, 2016
With the amount of data in the world exploding, big data could generate significant value in the field of infectious disease. The Forum on Microbial Threats determined that the broader applications and implications of big data in these areas ought to be explored, where “big data” refers to any voluminous amount of structured, semi-structured, and unstructured data that has the potential to be mined for insights and information.
The Ebola Epidemic in West Africa: Proceedings of a ...
Released: December 06, 2016
The most recent Ebola epidemic that began in late 2013 alerted the entire world to the gaps in infectious disease emergency preparedness and response. Building on previous outbreak workshops, the Forum on Microbial Threats convened this workshop to understand the recent developments in incidence, prevalence, and intervention strategies used to mitigate the disease in an increasingly interconnected world. Recognizing the opportunity to learn from the countless lessons of this epidemic, this workshop discussed the challenges to successful outbreak responses at the scientific, clinical, and global health levels.