Examination of the Evolving Science in Dietary Supplements
From a retrospective viewpoint, an expert committee of the Institute of Medicine, The National Academies, was appointed to review selected case studies of diet/health relationships identified as important in the Diet and Health report of 1989 with relevance to dietary supplements. The extent to which subsequent scientific evidence from the peer-reviewed literature used in the published Dietary Reference Intakes reports agrees with the preliminary evidence used to support the relationship identified originally in the 1989 review, or modifies significantly the original hypotheses and preliminary conclusions, was determined.
Based on the review of these studies, the analysis included characteristics of research that appeared to have a high probability of predicting future confirmation by new science in support of a diet and health relationship over time. It also included characteristics of information useful to consumers regarding the health effects of such food components or nutrients that allowed them to make scientifically informed judgments regarding the role that a specific food component or nutrient plays in health.