Dietary Reference Intakes for Vitamin D and Calcium
Activity News and Announcements
An IOM committee was named to undertake a study to assess current relevant data and update as appropriate the Dietary Reference Intakes for vitamin D and calcium. The review was to consider indicators for chronic disease risk reduction as well as other health outcomes. The study also was to incorporate, as appropriate, systematic evidence-based reviews of the literature and be organized as a risk assessment. Indicators for adequacy and excess were to be selected based on the strength and quality of the evidence and the demonstrated public health significance, taking into consideration sources of uncertainty in the evidence.
Specifically, in carrying out its work, the committee was asked to:
(1) Review evidence on indicators of adequacy and on indicators of adverse effects from excess intake relevant to the general US and Canadian population, including for groups whose needs for or sensitivity to the nutrient may be affected by levels of skin pigmentation, and by particular conditions which are widespread in the population such as obesity or age-related chronic diseases. Special groups under medical care whose needs or sensitivities are affected by rare genetic disorders or diseases and their treatments will be excluded.
(2) Consider systematic evidenced-based reviews including those made available by the sponsors as well as others and carefully document the approach used by the committee to carry out any of its own literature reviews.
(3) Regarding selection of indicators upon which to base DRI values for adequate intake, give priority to selecting indicators of adequacy for the various age, gender, and lifestage groups that will allow for the determination of an Estimated Average Requirement.
(4) Regarding selection of indicators upon which to base DRI values for upper levels of intake, give priority to examining whether a critical adverse effect can be selected that will allow for the determination of a so-called benchmark intake.
(5) Update DRI values, as appropriate, using a risk assessment approach that includes (i) identification of indicators of adequacy and hazard, (ii) selection of the indicators of adequacy and the critical adverse effect, (iii) intake-response assessment, (iv) dietary intake assessment, and (v) risk characterization.
(6) Identify research gaps to address the uncertainties identified in the process of deriving the reference values and evaluating their public health implications.
Announcement of Report Release
The report “Dietary Reference Intakes for Calcium and Vitamin D” was released on November 30, 2010.
The first meeting of the committee was held March 26-27, 2009 in Washington, DC. This meeting included an open session during which the study sponsors presented their perspectives to the committee.
The second committee meeting was held August 4-5, 2009 in Washington, DC. This meeting included an Information-Gathering Workshop on August 4, 2009.
The third committee meeting was held September 9-10, 2009 in Washington, DC. This meeting was a closed meeting.
The fourth committee meeting was held October 22-23, 2009 in Washington, DC. This meeting was a closed meeting, with an open session to address national survey design held on October 22, 2009.
The fifth committee meeting was held November 19-20, 2009 in Washington, DC. This meeting was a closed meeting with an open session on November 19th to discuss the role of vitamin D and calcium in kidney function, neophrocalcinosis, and nephrolithiasis.
The sixth committee meeting was held January 5-6, 2010 in Washington, DC. This meeting was a closed meeting.
The seventh committee meeting was held February 25-26, 2010 in Washington, DC. This meeting was a closed meeting.
The final committee meeting was held March 25-26, 2010 in Washington, DC. This meeting was a closed meeting.
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