The National Academies of Sciences, Engineering and Medicine

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The National Academy of Sciences and the National Academy of Medicine launched this initiative to inform decision-making related to recent advances in human gene-editing research. [Learn about related Academies’ studies and reports on genetic research]

Now Available: Archived February Webinar About Developments and Advancements in Human Genome Editing  

With the recent scientific advances making genome editing more efficient, precise, and flexible than ever before came an explosion of interest from around the globe in the possible ways human genome editing can improve human health. As part of the Human Gene-Editing Initiative, the National Academy of Sciences and National Academy of Medicine released a consensus study report last year exploring the scientific underpinnings of human gene-editing technologies, their potential applications in biomedical research and medicine, and the clinical, ethical, legal, and social implications of their use.

On Thursday, Feb. 22, 2018, NAS/NAM and the Biotechnology Innovation Organization (BIO) co-hosted a webinar to learn about issues and recommendations discussed in the 2017 NAS/NAM report, breakthroughs and next steps in gene editing of somatic cells, and the regulatory framework for therapies that make use of genome editing.

Participants in the webinar included:

Matthew Porteus, Stanford University (consensus study committee member)
Sandy Macrae, Sangamo Therapeutics
Peter Marks, U.S. Food and Drug Administration

Click here for the archived webinar | Slides from the webinar

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About This Initiative

Powerful new gene-editing technologies, such as CRISPR-Cas9, hold great promise for advancing science and treating disease, but they also raise concerns and present complex challenges, particularly because of their potential to be used to make genetic changes that could be passed on to future generations, thereby modifying the human germline.

In keeping with the Academies' past leadership on controversial new areas of genetic research, such as recombinant DNA technology, human embryonic stem cell research, human cloning, and “gain-of-function” research, the National Academy of Sciences and the National Academy of Medicine's human gene-editing initiative will provide researchers, clinicians, policymakers, and societies around the world with a comprehensive understanding of human gene editing to help inform decision-making about this research and its application.

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