The National Academies of Sciences, Engineering and Medicine

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The Academies have provided leadership in the past on controversial new areas of genetic research, such as recombinant DNA technology, human embryonic stem cell research, human cloning, and “gain-of-function” research. In keeping with these past efforts, the National Academy of Sciences and the National Academy of Medicine have launched a new initiative to inform decision making related to recent advances in human gene-editing research. [Learn about related Academies’ studies and reports on genetic research]

The initiative includes an international summit to convene global experts to discuss the scientific, ethical, and governance issues associated with human gene-editing research, as well as a comprehensive study by a multidisciplinary, international committee that will examine the scientific underpinnings and clinical, ethical, legal, and social implications of human gene editing. The committee will issue a report in 2016 with findings and recommendations for the responsible use of human gene-editing research. 


Latest News

Slides and Videos from the April Meeting in Paris
The consensus committee hosted a public meeting in Paris on April 29, focusing on the principles underlying human gene editing governance and policy. This event was held one day after a workshop on the current scientific activities and regulatory landscape for human gene editing in the European Union, organized by the Federation of European Academies of Medicine. Presentation slides and videos of the talks are now available online.

Slides and Videos from the February Meeting
On Feb. 11, the NAS/NAM Human Gene Editing consensus committee heard input from select stakeholder groups, including public engagement experts, affected communities, industry, regulatory bodies, and members of the public who came to share their perspectives. Presentation slides and recorded videos of the talks and discussions are now available online.

Summary of International Summit Now Available
A Meeting in Brief is now available that summarizes the December International Summit on Human Gene editing.

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About This Initiative

Powerful new gene-editing technologies, such as CRISPR-Cas9, hold great promise for advancing science and treating disease, but they also raise concerns and present complex challenges, particularly because of their potential to be used to make genetic changes that could be passed on to future generations, thereby modifying the human germline.

The National Academy of Sciences and the National Academy of Medicine's human gene-editing initiative will provide researchers, clinicians, policymakers, and societies around the world with a comprehensive understanding of human gene editing to help inform decision making about this research and its application.

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